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Association between the pH and clinicopathological characteristics of lung cancer tissue
https://iuhw.repo.nii.ac.jp/records/866
https://iuhw.repo.nii.ac.jp/records/86617433971-a90d-4962-8bb7-d63d8ed30b33
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
本文(PDF) (418.5 kB)
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| Item type | 学術雑誌論文 / Journal Article(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2017-11-15 | |||||||||
| タイトル | ||||||||||
| タイトル | Association between the pH and clinicopathological characteristics of lung cancer tissue | |||||||||
| タイトル | ||||||||||
| タイトル | Association between the pH and clinicopathological characteristics of lung cancer tissue | |||||||||
| 言語 | en | |||||||||
| 言語 | ||||||||||
| 言語 | eng | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | journal article | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | 水素イオン指数 | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | 微小環境 | |||||||||
| キーワード | ||||||||||
| 主題Scheme | Other | |||||||||
| 主題 | 低酸素誘導性因子 | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | hydrogen ion exponent | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | microenvironment | |||||||||
| キーワード | ||||||||||
| 言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | hypoxia-inducble factor | |||||||||
| 著者 |
澤田, 貴裕
× 澤田, 貴裕
|
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| 著者別名 | ||||||||||
| 姓名 | Sawada, Takahiro | |||||||||
| 内容記述 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | Recent studies have shown that cancer cells surviving in a microenvironment characterized by hypoxia, a low pH, and a low glucose level have the ability to adapt to these adverse conditions. We measured the pH in the central tumor area of primary lung cancer, and evaluated its association with clinicopathological factors. There was a negative correlation between the tumor size and pH; with an increase in the tumor size, the pH decreased. In addition, pH in lung adenocarcinoma was negatively correlated with the expression of tumor markers, although the correlation was not significant. Cancer cells grow at a markedly low pH compared with the physiological environment. There is a possibility that this low pH is a microenvironment that is appropriate rather than adverse for the proliferative ability of cancer cells. | |||||||||
| 書誌情報 |
国際医療福祉大学学会誌 en : Journal of the International University of Health and Welfare 巻 22, 号 2, p. 53-59, 発行日 2017-10-06 |
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| 出版者 | ||||||||||
| 出版者 | 国際医療福祉大学学会 | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | ISSN | |||||||||
| 収録物識別子 | 21863652 | |||||||||
| 書誌レコードID（NCID） | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| 収録物識別子 | AA12537130 | |||||||||
| 著者版フラグ | ||||||||||
| 値 | publisher | |||||||||
