@article{oai:iuhw.repo.nii.ac.jp:00000189,
 journal = {国際医療福祉大学紀要, Bulletin of International University of Health and Welfare},
 month = {Aug},
 note = {アルツハイマー型痴呆患者の疾病初期段階での特徴を明らかにすることを目的として、見当識・記憶・言語・視空間認知・構成の4領域から構成される神経心理検査バッテリー(老研版高次脳機能検査)を15例のアルツハイマー型痴呆疑い患者(DAT疑い群)と笹沼ら(1985;1987;1988)の研究での健常高齢者(健常群)に施行し、検査成績の比較検討を行った。その結果、(1)DAT疑い群は、記憶の下位検査の「物語の遅延再生(長期記憶/エピソード記憶)」および「検討識」の生成期において、健常群に比べ有意に低い成績を示した。しかし、(2)言語と視空間認知・構成の領域では両群間で顕著な差は認められなかった。この結果よりDAT疑い群の最も顕著な特徴は、エピソード記憶の障害と軽度の見当識障害であると考えられた。, A series of neuropsychological tests covering four broad domains : orientation, memory, linguistic functions, and visuospatial-constructive abilities, was administered to 15 patients with Possiple Alzheimer disease (PAD ; criteria of NINCDS-ADRDA work group, 1984), and the obtained performance data were compaired with those of the normal elderly studied by Sasanuma and her colleagues (1985;1987;1988). Major findings included the following : (1)PAD patients as a group performed significantly more poorly than the age matched normal elderly group on the test of delayed story recall and orientation. On the test of delayed story recall, none of the PAD patients could even remember that they had heard the story 30 minutes before. (2)On the test of linguistic functions and visuospatial-constructive abilities, on the other hand, there was no significant difference in performance between the two groups. These findings, taken together, indicate that most salient single neuropsychological feature of the PAD patients is marked impairment in episodic memory. On the basis of the present study, the pattern of impairment exhibited by these patients may be regarded as reflecting an early stage of DAT, although there are some alternative possibilities that some patients represent (a)atypical cases of DAT characterized by progressive memory impairment accompanied by no other cognitive disorders, or (b)Age-Associated Memory Impairment (AAMI) described by Crook et al.(1986). Differential diagnosis among these alternative cases will require longitudinal neuropsychological investigations with special focuses on the types and severity levels of memory impairment in each patient.},
 pages = {13--22},
 title = {アルツハイマー型痴呆疑い患者における高次脳機能検査の成績},
 volume = {1},
 year = {1996}
}